In Part 1 of this article I introduced
the endocrine system. The overview
continues here. Following is a brief
overview of the glands, the hormone(s) they produce, and the function of those
hormones.
Future articles will provide
more details.
Pineal
gland
Melatonin – sleep regulation, internal
clock.
Hypothalamus
Produces several releasing hormones and
inhibiting hormones. The releasing
hormones stimulate the anterior pituitary to release hormones. The inhibiting hormones stop the anterior
pituitary from secreting hormones. The major releasing hormones are:
Thyroid releasing hormone (TRH) –
stimulates pituitary to release TSH.
Corticotropin releasing hormone (CRH) –
stimulates pituitary to release ACTH.
Gonadotropin releasing hormone (GnRH) –
stimulates pituitary to release FSH and LH.
Pituitary
The pituitary
gland produces different hormones from its anterior and posterior parts.
The anterior
pituitary secretes hormones to stimulate additional hormones. It receives its instructions from the
hypothalamus.
Thyroid
stimulating hormone (TSH) – stimulates secretion of thyroid hormones.
Adrenocorticotropic hormone (ACTH) - stimulates secretion of adrenal
cortex hormones.
Follicle-stimulating hormone (FSH) – In females stimulates development of
ovarian follicles and secretion of estrogen; in males stimulates testes to grow
and produce sperm.
Luteinizing hormone (LH) – In females stimulates maturation of ovarian
follicle and ovum; stimulates secretion of estrogen; triggers ovulation; and stimulates
development of corpus luteum. In males
stimulates interstitial cells of the testes to secrete testosterone.
Growth hormone (GH) - Stimulates growth in all organs; mobilizes food
molecules, causing an increase in blood glucose concentration.
Prolactin (lactogenic hormone) - Stimulates breast development during
pregnancy and milk secretion after pregnancy.
The posterior pituitary secretes ADH and oxytocin.
Antidiuretic hormone (ADH) - Stimulates retention of water by the kidneys.
Oxytocin - Stimulates uterine contractions at the end of pregnancy;
stimulates the release of milk into the breast ducts; and plays a role in
sexual arousal in males and non-nursing females (sometimes called the “cuddling
hormone”).
Thyroid
Thyroxine (T4)
and Triiodothyronine (T3) – Stimulate the energy metabolism of all cells.
Calcitonin –
Inhibits the breakdown of bone; causes a decrease in blood calcium concentration.
Parathyroid
Parathyroid
hormone (PTH) – Stimulates the breakdown of bone; causes an increase in blood
calcium concentration.
Thymus
Thymosin –
Promotes development of immune system cells.
Pancreas
Glucagon –
Stimulates liver glycogenolysis, causing an increase in blood glucose
concentration.
Insulin –
Promotes glucose entry into all cells, causing a decrease in blood glucose
concentration.
Adrenal
Mineralocorticoids:
aldosterone – Regulates electrolyte and fluid homeostasis.
Glucocorticoids:
cortisol (hydrocortisone) - Stimulates gluconeogenesis, causing an increase in
blood glucose concentration; also have anti-inflammatory and anti-immunity,
anti-allergy effects.
Sex hormones -
the adrenals produce “female” hormones in males (estrogen, progesterone) and
“male” hormones in females (testosterone).
Epinephrine
(adrenaline) and norepinephrine - Prolong and intensify the sympathetic nervous
response during stress.
Ovary (Female)
Estrogen –
Promotes development and maintenance of female sexual characteristics.
Progesterone –
Promotes conditions required for pregnancy.
Testes (Male)
Testosterone –
Promotes development and maintenance of male sexual characteristics.
Fat Storing Cells
Leptin –
Controls how hungry or full we feel.
Bernard Rosen, PhD is a Nutrition
Consultant and Educator. He works with individuals, groups, and at corporations
to create individualized nutrition and wellness programs. His office is in
Mequon, WI. To learn more or to schedule an appointment, e-mail at bernie@brwellness.com, call (262)
389-9907 or go to www.brwellness.com.
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